ICSI stands for intracytoplasmic sperm injection. It is basically an advanced form of In Vitro fertilization carried out in the embryology laboratory. It is considered a boon for couples who are infertile due to male factor. This is a technique that improves the chances of pregnancy in cases of infertility caused due to male factors. In the process, each egg that has been retrieved is inseminated by a single sperm that is directly injected into the cytoplasm of the egg cell. This technique greatly improves the chances of fertilization of eggs and their development into the embryo and further stages. Once the insemination and fertilization are complete, rest other processes are carried basis the artificial reproductive technique recommended for the subject.
Major indications for ICSI are as follows:
- Male factor of low or very low sperm count.
- Asthenozoospermia or the condition of low motility of sperms.
- Azoospermia or the condition where sperm count is almost negligible.
- Teratozoospermia or condition where sperm morphology is poor.
- Oligozoospermia or condition of low concentration of sperm.
- Poor fertilization by IVF in the previous cycle.
Technology, for male Factor infertility.
In this process, each egg is injected with a sperm through a thin needle to aid the fertilization process.
ICSI as a technique has one of the highest success rates in comparison to many other similar techniques. The most advantageous factor of this technique happens to be the process of directly injecting a healthy sperm into the cytoplasm of the egg. This process almost guarantees fertilization of the egg. Basis the same, the success rate of fertilization by ICSI is around 70-80%. However, the success rate of the ART for which ICSI is been used as a sub-processes might vary. Further, the success rate of the process is highly individualized.
- Is the fertilization rate of ICSI better than IVF?
Yes, in the case of male factor infertility.
- What is the rate of fertilization of ICSI?
- Does ICSI technology always need to be coupled with the testicular sperm retrieval?
Yes, because testicular sperms are poor in count, motility.